Team
Ayellet Segrè, Ph.D.
Principal Investigator
Assistant Professor of Ophthalmology, Harvard Medical School
Assistant Scientist, Ocular Genomics Institute, Massachusetts Eye and Ear (MEE)
Co-Director, Biostatistics and Bioinformatics Core, MEE
Associate Member, Broad Institute of Harvard and MIT
Member of the Genotype-Tissue Expression (GTEx) Project Consortium
E-mail: ayellet_segre [at] meei.harvard.edu
Jacqueline Ohmura, Ph.D.
M.D. student at Harvard and MIT Health, Sciences and Technology (HST) MD program
Ph.D., Biological Engineering, MIT
B.S., Materials Engineering, Ohio State University, Columbus, OH
Co-mentored with Prof. Janey Wiggs, Mass. Eye and Ear, HMS
Jackie is using soft clustering analysis (non-negative matrix factorization) across genetic associations of known glaucoma loci with multiple endophenotypes of primary open angle glaucoma to identify pathogenic mechanisms and biological subtypes of glaucoma.
E-mail: Ohmura [at] mit.edu
Katherine Duchinski
Ph.D. student in the Bioinformatics and Integrative Genomics (BIG) Program, Harvard Medical School
B.S., Biology and Data Sciences, College Of Charleston, Charleston, SC
Katherine is interested in integrating human genetics, functional genomics, and small molecule perturbational expression profiles to identify new drug repurposing opportunities for complex eye diseases, such as glaucoma and age-related macular degeneration.
E-mail: kduchinski [at] g.harvard.edu
Puja Mehta, M.Sc.
Bioinformaticist
M.Sc., Bioinformatics, Northeastern University, Boston, MA
B.S., Biotechnology, Dayananda Sagar College of Engineering, Bengaluru, India
Puja is interested in using splicing QTLs in human retina to identify novel regulatory mechanisms that lead to age-related macular degeneration, and in integrating functional genomic and single cell data with GWAS to shed light on the causal mechanisms of eye disease.
E-mail: PAMEHTA [at] MEEI.HARVARD.EDU
Yuyang (Leo) Luo, Ph.D.
Bioinformaticist
Ph.D., Biomedical Engineering, Rutgers University, Newark, NJ
M.Sc., Electronic and information Engineering, Stevens Institute of Technology, Hoboken, NJ
B.S., Electronic and information Engineering, Wuhan University of Science and Technology, China
Co-advised with Dr. Elizabeth Rossin and Prof. Janey Wiggs, Mass. Eye and Ear, HMS
E-mail: YLUO14 [at] MEEI.HARVARD.EDU
Songtao Xu, M.Sc.
Bioinformaticist; Previously MSc internship student
M.Sc. student in Biomedical Informatics Program, Harvard Medical School
B.A. in Computational Biology; Mathematical Sciences: Statistics, Colby College, Waterville, ME
Alumni
Alumni: Andrew Hamel, M.Sc.
Bioinformatics Analyst, NBACC, Battelle National Biodefense Institute
M.Sc., Bioinformatics Program at Boston University
B.A., Biochemistry and Molecular Biology; Minor in Mathematics, The College of Wooster, Wooster, Ohio
Alumni: John Rouhana, M.Sc.
Senior Research Associate at Gritstone Oncology
M.Sc., Bioinformatics, Northeastern University, Boston, MA
B.Sc., Premedical and Health Studies, MCPHS University, Boston, MA
Alumni: Jiali Wang, M.Sc., Ph.D.
Senior Principal Biostatistician at Novartis
Ph.D., Statistics, Australian National University, Australia
M.Sc.., Statistics, Australian National University, Australia
B.S., Mathematics, Capital Normal University, China
Alumni: Arushi Shrivastava, M.Sc.
Senior Data Scientist, Bioinformatician, Johnson & Johnson Innovative Medicine
M.Sc. in Bioinformatics Program at Boston University
B.S. in Biotechnology, JECRC University, Jaipur, Rajasthan, India
Alumin: Ashwathy Nair, M.Sc.
Bioinformaticist
M.Sc., Bioinformatics, Northeastern University, Boston, MA
B.E in Biotechnology, SIES Graduate School of Technology, Mumbai, India