*** Position Opportunities ***

We are seeking talented postdoctoral fellows, graduate students and biostatisticians/bioinformaticists excited about using computational genomics approaches, in partcular single cell genomics, human genetics and functional genomics, to study the genetic and biological causes of complex eye diseases, to join our lab!  Interested applicants should send their CV, a cover letter describing past experience and research interests, and contact information for 3 references to Ayellet Segrè: ayellet_segre [at] meei [dot] harvard [dot] edu.

For a more detailed description of the Postdoctoral fellow position click here

Segrè Lab holiday lunch 2023!

1/2024 - Ayellet Segrè received the Research to Prevent Blindness (RPB) / The Glaucoma Foundation 2023 Career Advancement Award on "Integrating cell type-specific genetic regulation in the outflow pathway, retina and optic nerve head with genetic associations to uncover causal mechanisms for glaucoma".

5/2023 - Congratulations to Jackie Ohmura for completing her MD Degree with Honors in a Special Field, magna cum laude, Harvard-MIT HST MD program. Thesis: "Soft clustering analysis of primary open angle glaucoma loci and their association with multiple endophenotypes uncovers pathophysiological and cellular mechanisms of disease". 

3/2023 Ayellet Segrè presented at the NEI symposium on "Emerging Horizons in Retinal Genetics, Biology and Disease Agenda" on integrating genetic variation and single cell genomics to uncover complex retinal disease mechanisms.

10/2022 – Katherine Duchinski a PhD student in the lab was awarded Reviewers’ Choice for her poster "Genomic-based drug-repurposing screen approach discovers potential novel therapies for primary open-angle glaucoma" at the American Society for Human Genetics (ASHG) 2022 meeting.

06/01/2020 – 05/31/2025 – Lab awarded NIH/NEI R01 grant EY031424-01 (PI: Segrè)  – “Uncovering Novel Biological Processes and Pathogenic Mechanisms for Glaucoma”

7/1/2019 - 6/30/2022 – Segrè is a co-PI on a Chan Zuckerberg Initiative Seed Network grant aimed at building a Human Cell Atlas of the eye from birth to old age, using single cell RNA-sequencing:

May 1, 2019 -Segrè presented a talk titled “Integrative analysis of GWAS and eQTLs proposes new genetic associations and causal genes for Primary Open Angle Glaucoma” at the Association for Research in Vision and Ophthalmology (ARVO) 2019 conference.

March 8. 2018 – Segrè presented on Age-related macular degeneration genetics at the 38th Annual meeting of the Israeli Society for Vision and Eye Research (ISVER)